Implementing the National Academy's Vision and Strategy for Toxicity Testing: Opportunities and Challenges Under the U.S. Toxic Substances Control Act

Written by: Paul A. Locke and D. Bruce Myers, Jr. Published in Journal of Toxicology and Environmental Health on 6/21/10

In 2007, the U.S. National Academy of Sciences, National Research Council (NRC), issued the report Toxicity Testing in the 21st Century: A Vision and a Strategy. This report, which was commissioned by the U.S. Environmental Protection Agency (EPA), called for the U.S. EPA to develop a new approach for how this agency evaluates the toxicity of compounds. The report recommended that the agency move from its current testing system, which is based largely on traditional toxicology, to a testing system that is based primarily on human cell lines and in vitro systems… Read the rest of the article in the Journal of Toxicology and Environmental Health.

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Engagement of Scientists with the Public and Policymakers to Promote Alternative Methods

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A Replacement-first Approach to Toxicity Testing is Necessary to Successfully Reauthorize TSCA